Thyroglobulin may be undetectable in the serum of patients with metastatic disease secondary to differentiated thyroid carcinoma. Follow-up of differentiated thyroid carcinoma
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چکیده
منابع مشابه
Serum thyroglobulin determination in the follow-up of patients with differentiated thyroid carcinoma.
Thyroglobulin (Tg) is produced only by thyroid follicular cells. Following total thyroid ablation, it should be undetectable in serum and any detectable level then indicates the persistence or recurrence of neoplastic disease. This is the basis for the use of Tg as a postoperative tumor marker in the follow-up of thyroid cancer patients (1). The aim of follow-up is the early detection of persis...
متن کاملHow to manage patients with undetectable thyroglobulin but thyroid residue after radioiodine ablative therapy in differentiated thyroid carcinoma, retreatment or observation?
Introduction:Differentiated thyroid carcinoma (DTC) follow-up after thyroidectomy and radioiodine-ablation is performed mainly by thyroglobulin (Tg), diagnostic iodine-131 whole body scan (DxWBS) and sonography. Some patients with undetectable Tg have thyroid-bed uptake after ablation in whom decision making regarding the need for retreatment is still controversial. Me...
متن کاملEvaluation of Treatment of Differentiated Carcinoma of Thyroid.
The treatment of patient with differentiated carcinoma of thyroid consists of three stages, surgery, I 1.1.i ablation and hormone therapy. To avoid the problems mentioned in the article, initially the patient should have thyroid scan, T.1 , T4, thyroglobulin estimation and a chest x-ray, prior to surgery which should be carried out by a competent surgeon, in order that total thyroidectomy can b...
متن کاملThyroglobulin value in patients surgically treated for differentiated thyroid carcinoma
Gostimir MIKAČ Faculty of Medicine Save Mrkalja 22 78000 Banja Luka Republic of Srpska Bosnia and Herzegovina [email protected] SUMMARY Introduction Thyroglobulin is composed glycoprotein, and it is synthesized by follicular cells of the thyroid gland. Treatment of differentiated thyroid carcinomas involves total thyroidectomy followed by radioiodine ablation of a potential remaining tissue. The m...
متن کاملHeterophile antibodies may falsely increase or decrease thyroglobulin measurement in patients with differentiated thyroid carcinoma.
BACKGROUND To examine the prevalence of significant interference from heterophile antibodies (HAb) in the measurement of serum thyroglobulin (Tg), we evaluated a large cohort of samples from patients with differentiated thyroid carcinoma (DTC). METHODS Serum Tg measurements were performed in 406 serum samples before and after incubation of each serum sample in heterophile-blocking tubes (HBT)...
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ژورنال
عنوان ژورنال: Cancer
سال: 1984
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19841015)54:8<1625::aid-cncr2820540825>3.0.co;2-0